One of the victims was pronounced dead at the scene; the police did not release his identity on Saturday. The other two victims, a woman, 21, and man, 22, were not injured.
Anyone with information is asked to call the St. Louis Police Homicide Division at 314-444-5371, or make an anonymous tip to CrimeStoppers at 866-371-8377.
At least six other people were victims of shootings in two other city neighborhoods on Friday night, police said. Three of them were injured.
On the 3300 block of Nebraska Avenue, in Benton Park West, a 15-year-old boy was walking in the area about 6:20 p.m. when two suspects approached and shot him in his face and torso, and fled. He was taken by ambulance to a hospital where he was listed as in critical but stable condition. The assailants were described as two Black teenage boys, 15-18. One was between 5 feet, 10 inches and 6 feet, 2 inches, thin, with light skin, wearing a red hooded sweat shirt. The other was between 5 feet, 10 inches and 6 feet, thin, wearing a black hooded sweatshirt.
And about 11:28 p.m., police responded to a market on the 4900 block of St. Louis Avenue in the Kingsway East neighborhood and found an unoccupied car that had been shot up. Police later found the driver of the car fled on foot and later showed up at a hospital with a graze wound to his head; he was listed as in stable condition. Two women in another car also drove to a hospital; one of them had cuts to her head. She was in stable condition. Two women in a third car fled the shooting and crashed less than one-tenth of a mile away on the 3000 block of North Kingshighway. They were not injured.